Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 5/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29061084 | 0.99 | AGTR2 (0.48) | AGTR2LIPGTEAD3BCHETMEM97 | |
| SCHEMBL30937049 | 0.94 | AGTR2 (0.50) | AGTR2LIPGTEAD3BCHETMEM97 | |
| SCHEMBL21070250 | 0.78 | LIPG (0.35) | AGTR2LIPG | |
| SCHEMBL22284346 | 0.78 | AGTR2 (0.38) | AGTR2LIPGTEAD3MEN1GAA | |
| SCHEMBL7400688 | 0.77 | AGTR2 (0.46) | AGTR2TMEM97SIGMAR1 | |
| SCHEMBL26634961 | 0.77 | SMN1; SMN2 (0.46) | AGTR2MEN1KMT2A | |
| SCHEMBL28516435 | 0.76 | LIPG (0.34) | AGTR2LIPGKMT2A | |
| SCHEMBL21997606 | 0.76 | AGTR2 (0.38) | AGTR2LIPGMEN1KMT2A | |
| SCHEMBL21458588 | 0.76 | LIPG (0.34) | LIPGKMT2AEPHX2 | |
| SCHEMBL21458596 | 0.75 | STS (0.53) | LIPGGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072178-A1 | COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF | (주)사이러스테라퓨틱스 | 2024-04-04 | — | — | WO | disclosed |