Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.45 |
| ▸ | INSR | P06213 | 4/20 | 0.45 |
| ▸ | IGF1R | P08069 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | ROS1 | P08922 | 1/20 | 0.43 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.43 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30937048 | 0.90 | EGFR (0.55) | EGFRMETALKINSRZAP70 | |
| SCHEMBL30937117 | 0.87 | EGFR (0.52) | EGFRMETALKINSRZAP70 | |
| SCHEMBL30936950 | 0.87 | ALK (0.55) | EGFRMETALKINSR | |
| SCHEMBL30936792 | 0.85 | EGFR (0.59) | EGFRMETALKINSRIGF1R | |
| SCHEMBL30936799 | 0.84 | EGFR (0.49) | EGFRMETALKINSRZAP70 | |
| SCHEMBL30936830 | 0.82 | EGFR (0.57) | EGFRMETALKINSRIGF1R | |
| SCHEMBL30936861 | 0.82 | EGFR (0.62) | EGFRMETALKINSRIGF1R | |
| SCHEMBL30936873 | 0.80 | EGFR (0.50) | EGFRMETALKINSRIGF1R | |
| SCHEMBL30936957 | 0.79 | EGFR (0.67) | EGFRALKROS1ZAP70 | |
| SCHEMBL30937107 | 0.79 | EGFR (0.67) | EGFRALKROS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072178-A1 | COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF | (주)사이러스테라퓨틱스 | 2024-04-04 | — | — | WO | disclosed |