Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | ZAP70 | P43403 | 4/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.46 |
| ▸ | INSR | P06213 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ROS1 | P08922 | 1/20 | 0.44 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30936997 | 0.91 | EGFR (0.51) | EGFRZAP70ALKINSR | |
| SCHEMBL27076108 | 0.83 | EGFR (0.62) | EGFRMETZAP70ALKINSR | |
| SCHEMBL30936238 | 0.80 | PTK2 (0.49) | EGFRALK | |
| SCHEMBL30936853 | 0.80 | EGFR (0.51) | EGFRMETZAP70ALKINSR | |
| SCHEMBL24817687 | 0.78 | ALK (0.63) | EGFRALKINSRAURKAIGF1R | |
| SCHEMBL26379415 | 0.78 | EGFR (0.69) | EGFRALKINSRAURKAIGF1R | |
| SCHEMBL30936779 | 0.78 | EGFR (0.56) | EGFR | |
| SCHEMBL30936863 | 0.77 | EGFR (0.59) | EGFRZAP70 | |
| SCHEMBL26379427 | 0.76 | EGFR (0.67) | EGFRMETZAP70ALKINSR | |
| SCHEMBL30936861 | 0.76 | EGFR (0.62) | EGFRMETALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072178-A1 | COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF | (주)사이러스테라퓨틱스 | 2024-04-04 | — | — | WO | disclosed |