Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30937361 | 0.93 | DDB1 (0.36) | DDB1CRBNPARP1SIGMAR1TLR2 | |
| SCHEMBL31341963 | 0.84 | DHODH (0.33) | — | |
| SCHEMBL35212168 | 0.83 | TTR (0.31) | — | |
| SCHEMBL30937280 | 0.81 | DCAF1 (0.38) | DDB1CRBNPARP1SUCNR1 | |
| SCHEMBL31342626 | 0.80 | PRKAB2 (0.33) | — | |
| SCHEMBL35211555 | 0.80 | PRKAB2 (0.33) | — | |
| SCHEMBL31342230 | 0.80 | PRKAB2 (0.33) | — | |
| SCHEMBL30937278 | 0.79 | DDB1 (0.33) | DDB1CRBNPARP1IDO1 | |
| SCHEMBL31342430 | 0.78 | CYP4A11 (0.39) | — | |
| SCHEMBL35211910 | 0.73 | CYP4A11 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608807-A1 | PROTEIN DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024092009-A1 | PROTEIN DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |