SCHEMBL35211555

SCHEMBL35211555

Cc1c(F)ccc(F)c1-c1c(C(=O)O)c[nH]c1C(=O)c1ccc(CCOCCOCCOCCOCCO)cc1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PRKAB2 O43741 6/20 0.33
▸ PRKAG1 P54619 6/20 0.33
▸ PRKAA2 P54646 6/20 0.33
▸ PRKAA1 Q13131 6/20 0.33
▸ PRKAG3 Q9UGI9 6/20 0.33
▸ PRKAG2 Q9UGJ0 6/20 0.33
▸ PRKAB1 Q9Y478 6/20 0.33
▸ DHODH Q02127 1/20 0.30
▸ RARA P10276 1/20 0.30
▸ RARB P10826 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31342626 1.00 PRKAB2 (0.33) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL31342230 1.00 PRKAB2 (0.33) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL31341963 0.93 DHODH (0.33) PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
SCHEMBL35211913 0.91 CYP4A11 (0.35) DHODH
SCHEMBL35211571 0.91 CYP4A11 (0.35) DHODH
SCHEMBL35211910 0.91 CYP4A11 (0.35) DHODH
SCHEMBL35212168 0.85 TTR (0.31) RARARARB
SCHEMBL31342430 0.84 CYP4A11 (0.39) DHODH
SCHEMBL35212228 0.82 AR (0.34) —
SCHEMBL30879998 0.79 AKR1C3 (0.38) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-05-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF STAT6, NCOR2, NCOR1 PRKAB2 2436/4885PRKAG1 3458/4885PRKAA2 2363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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