SCHEMBL30937482

SCHEMBL30937482

CC(C)(C)OC(=O)Nc1ccc2[nH]ccc2c1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.56
MAOB P27338 6/20 0.56
NPC1 O15118 4/20 0.55
RAB9A P51151 4/20 0.55
MAPT P10636 3/20 0.55
NOTUM Q6P988 1/20 0.51
EPHX1 P07099 2/20 0.50
PRKCI P41743 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2076885 1.00 MAOA (0.56) MAOAMAOBNPC1RAB9AMAPT
SCHEMBL15213102 0.89 MAOA (0.56) MAOAMAOBNOTUM
SCHEMBL7038134 0.85 MAOB (0.61) MAOAMAOBNPC1RAB9AMAPT
SCHEMBL31005743 0.82 ROCK2 (0.60)
SCHEMBL2724096 0.81 MAOA (0.59) MAOAMAOBNPC1RAB9AMAPT
SCHEMBL15829326 0.81 CFTR (0.53) MAOAMAOBNPC1RAB9AMAPT
SCHEMBL7483289 0.80 MAOA (0.66) MAOAMAOBNPC1RAB9AMAPT
SCHEMBL8533952 0.80 NPC1 (0.58) MAOAMAOBNPC1RAB9AMAPT
SCHEMBL16756055 0.79 MAOB (0.58) MAOAMAOBNPC1RAB9AMAPT
SCHEMBL5177372 0.79 MAOB (0.83) MAOAMAOBNPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4629988-A1 DERIVATIVES OF INDOLE FOR THE TREATMENT OF CANCER AND INFECTIONS Centre National de la Recherche Scientifique (FR) 2025-10-15 EP disclosed
WO-2024121072-A1 DERIVATIVES OF INDOLE FOR THE TREATMENT OF CANCER AND INFECTIONS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2024-06-13 WO disclosed