Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CD38 | P28907 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30938010 | 1.00 | HTT (0.59) | HTTMAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30938011 | 1.00 | HTT (0.59) | HTTMAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30938025 | 0.89 | TBXAS1 (0.48) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30938046 | 0.88 | TBXAS1 (0.47) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30938030 | 0.87 | CYP1A2 (0.61) | HTTMAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL476250 | 0.83 | HTT (0.72) | HTTMAPTCYP3A4KDM4EABL1 | |
| SCHEMBL30938029 | 0.82 | RAB9A (0.47) | HTTMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30938021 | 0.81 | KCNQ3 (0.47) | HTTMAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30938022 | 0.81 | CD38 (0.48) | HTTMAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30938044 | 0.81 | SIRT2 (0.45) | HTTMAPTCD38ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615836-A1 | INHIBITORS OF CYCLIC ADP RIBOSE HYDROLASE METHODS OF USE THEREOF | Flagship Pioneering Innovations VI, LLC (US) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024102924-A1 | INHIBITORS OF CYCLIC ADP RIBOSE HYDROLASE METHODS OF USE THEREOF | FLAGSHIP PIONEERING INNOVATIONS, VI, LLC (US) | 2024-05-16 | — | — | WO | disclosed |