Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.44 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ADAM10 | O14672 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | BCL9 | O00512 | 3/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17479229 | 0.91 | TPSAB1 (0.52) | TPSAB1TPSD1TPSG1CHRNB2CHRNA3 | |
| SCHEMBL29703407 | 0.88 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1CA2ADAM10 | |
| SCHEMBL29703400 | 0.88 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1CA2ADAM10 | |
| SCHEMBL28288403 | 0.88 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1CA2ADAM10 | |
| SCHEMBL17479093 | 0.87 | TPSAB1 (0.44) | TPSAB1TPSD1TPSG1CHRNB2CHRNA3 | |
| SCHEMBL28131722 | 0.83 | TPSAB1 (0.39) | TPSAB1TPSD1TPSG1CHRNB2CHRNA3 | |
| SCHEMBL28131011 | 0.83 | TPSAB1 (0.39) | TPSAB1TPSD1TPSG1CHRNB2CHRNA3 | |
| SCHEMBL951611 | 0.81 | TPSAB1 (0.58) | TPSAB1TPSD1TPSG1CHRNB2CHRNA3 | |
| SCHEMBL28796541 | 0.81 | TPSAB1 (0.55) | TPSAB1TPSD1TPSG1CHRNB2CHRNA3 | |
| SCHEMBL28067576 | 0.81 | TPSAB1 (0.55) | TPSAB1TPSD1TPSG1CHRNB2CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076607-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |