Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 6/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 6/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 6/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | ADAM10 | O14672 | 4/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29703400 | 1.00 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1HSD11B1CA2 | |
| SCHEMBL29703407 | 1.00 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1HSD11B1CA2 | |
| SCHEMBL5623233 | 0.90 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1HSD11B1CA2 | |
| SCHEMBL12520131 | 0.90 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1HSD11B1CA2 | |
| SCHEMBL30938286 | 0.88 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1HSD11B1CA2 | |
| SCHEMBL28067576 | 0.87 | TPSAB1 (0.55) | TPSAB1TPSD1TPSG1HSD11B1CA2 | |
| SCHEMBL29788930 | 0.85 | HSD11B1 (0.49) | TPSAB1TPSD1TPSG1HSD11B1CA2 | |
| SCHEMBL26124912 | 0.84 | TPSAB1 (0.55) | TPSAB1TPSD1TPSG1HSD11B1CA2 | |
| SCHEMBL4879948 | 0.83 | HSD11B1 (0.46) | TPSAB1TPSD1TPSG1HSD11B1CA2 | |
| SCHEMBL28212050 | 0.79 | HSD11B1 (0.53) | TPSAB1TPSD1TPSG1HSD11B1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641895-A | Indole compounds substituted with [1, 2, 4] triazolo [1, 5-a ] pyridyl | 百时美施贵宝公司 | 2019-04-16 | — | — | CN | disclosed |