Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | CASP1 | P29466 | 6/20 | 0.53 |
| ▸ | CASP7 | P55210 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3325765 | 0.89 | KDM4E (0.61) | KDM4EALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL6955134 | 0.81 | POLB (0.68) | POLBLMNATSHRMAPTMAPK1 | |
| SCHEMBL5333546 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL30938463 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL7416441 | 0.79 | POLB (0.64) | POLBLMNATSHRMAPTMAPK1 | |
| SCHEMBL7132512 | 0.79 | POLB (0.75) | POLBLMNATSHRMAPTMAPK1 | |
| SCHEMBL5476653 | 0.76 | CACNA1F (0.62) | KDM4EPOLBLMNAAGTR1TSHR | |
| SCHEMBL30938456 | 0.75 | GAA (0.67) | KDM4EALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL31634787 | 0.75 | GAA (0.67) | KDM4EALDH1A1HPGDHTTNPSR1 | |
| SCHEMBL5312208 | 0.74 | KDM4E (0.66) | KDM4EALDH1A1HPGDHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260102387-A1 | IMMUNOSUPPRESSIVE COMPOUNDS | UNIV BASEL (CH) | 2026-04-16 | — | — | US | disclosed |
| EP-4594304-A2 | IMMUNOSUPPRESSIVE COMPOUNDS | Universität Basel Vizerektorat Forschung (CH) | 2025-08-06 | — | — | EP | disclosed |
| CN-120202189-A | Immunosuppressant compounds | 巴塞尔大学 | 2025-06-24 | — | — | CN | disclosed |
| WO-2024069007-A2 | IMMUNOSUPPRESSIVE COMPOUNDS | UNIVERSITÄT BASEL (CH) | 2024-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260102387-A1 | IMMUNOSUPPRESSIVE COMPOUNDS | CHP1, BRD3, IRF3 | KDM4E 3376/4885ALDH1A1 4040/4885HPGD 4105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.