Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036198 | 1.00 | RAB9A (0.59) | RAB9APOLBMEN1KMT2AHTT | |
| SCHEMBL2190433 | 0.86 | POLB (0.59) | POLBMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL28007482 | 0.84 | CA1 (0.51) | RAB9APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL29268504 | 0.84 | RAB9A (0.60) | RAB9APOLBMEN1KMT2AHTT | |
| SCHEMBL6273868 | 0.83 | POLB (0.61) | RAB9APOLBMEN1KMT2AHTT | |
| SCHEMBL24499421 | 0.83 | NPC1 (0.59) | RAB9APOLBMEN1KMT2AHTT | |
| SCHEMBL31384714 | 0.83 | KMT2A (0.62) | POLBKMT2AALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL4005420 | 0.83 | ALDH1A1 (0.63) | MEN1KMT2AHTTALDH1A1TDP1 | |
| SCHEMBL21765662 | 0.83 | RAB9A (0.41) | RAB9APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL6267767 | 0.82 | POLB (0.59) | RAB9APOLBMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778311-B | Nitrogen-containing fused ring derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-06-04 | — | — | CN | disclosed |