Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29332240 | 1.00 | CYP11B1 (0.44) | CYP11B1CYP11B2CYP19A1TAAR1PTGES | |
| SCHEMBL25383372 | 0.78 | TAAR1 (0.49) | CYP11B1CYP11B2CYP19A1TAAR1PTGES | |
| SCHEMBL30938625 | 0.78 | CYP11B1 (0.44) | CYP11B1CYP11B2CYP19A1PTGESALOX5 | |
| SCHEMBL29333144 | 0.77 | PTGES (0.44) | CYP11B1CYP11B2CYP19A1TAAR1PTGES | |
| SCHEMBL29332326 | 0.76 | TAAR1 (0.42) | CYP11B1CYP11B2CYP19A1TAAR1MAOB | |
| SCHEMBL28748513 | 0.76 | SCN9A (0.48) | MAOBNOS3NOS2 | |
| SCHEMBL109903 | 0.75 | ALDH1A1 (0.48) | NOS3NOS2 | |
| SCHEMBL30354760 | 0.74 | TAAR1 (0.47) | CYP11B1CYP11B2CYP19A1TAAR1PTGES | |
| SCHEMBL30354770 | 0.74 | MAOB (0.71) | TAAR1MAOBPPARDPPARA | |
| SCHEMBL29332333 | 0.73 | TAAR1 (0.42) | CYP11B1CYP11B2CYP19A1TAAR1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |