Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HK1 | P19367 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24744893 | 0.89 | KDM4E (0.37) | TLR7KDM4EALDH1A1JAK2JAK1 | |
| SCHEMBL31090538 | 0.89 | KDM4E (0.37) | TLR7KDM4EALDH1A1JAK2JAK1 | |
| SCHEMBL30938924 | 0.89 | KDM4E (0.37) | KDM4EALDH1A1JAK2JAK1JAK3 | |
| SCHEMBL31090655 | 0.88 | TLR7 (0.37) | TLR7KDM4EALDH1A1JAK2JAK1 | |
| SCHEMBL24742725 | 0.88 | TLR7 (0.37) | TLR7KDM4EALDH1A1JAK2JAK1 | |
| SCHEMBL24744910 | 0.87 | ATR (0.37) | TLR7KDM4EALDH1A1JAK2JAK1 | |
| SCHEMBL24742722 | 0.87 | JAK2 (0.41) | TLR7KDM4EALDH1A1JAK2JAK1 | |
| SCHEMBL24744900 | 0.82 | ALDH1A1 (0.38) | TLR7KDM4EALDH1A1JAK2JAK1 | |
| SCHEMBL24744762 | 0.80 | PKN1 (0.47) | KDM4EALDH1A1SMN1; SMN2PTGER4MAPT | |
| SCHEMBL29893726 | 0.80 | PKN1 (0.47) | KDM4EALDH1A1SMN1; SMN2PTGER4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630414-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | Captor Therapeutics S.A. (PL) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121256-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2024-06-13 | — | — | WO | disclosed |