Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 1/20 | 0.47 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24744762 | 1.00 | PKN1 (0.47) | PKN1PKN2KDM4EALDH1A1PIK3CB | |
| SCHEMBL24744761 | 0.88 | KDM4E (0.46) | PKN1PKN2KDM4EALDH1A1PIK3CB | |
| SCHEMBL30952847 | 0.88 | KDM4E (0.46) | PKN1PKN2KDM4EALDH1A1PIK3CB | |
| SCHEMBL24745161 | 0.84 | PTGDR2 (0.50) | PKN1PKN2KDM4EPIK3CBLCK | |
| SCHEMBL30000721 | 0.84 | PTGDR2 (0.50) | PKN1PKN2KDM4EPIK3CBLCK | |
| SCHEMBL24745449 | 0.84 | CACNA1B (0.40) | PKN1PKN2KDM4EALDH1A1PTGER4 | |
| SCHEMBL24745728 | 0.83 | ALDH1A1 (0.37) | PKN1PKN2KDM4EALDH1A1MAPT | |
| SCHEMBL24744896 | 0.82 | KDM4E (0.36) | PKN1PKN2KDM4EALDH1A1PTGER4 | |
| SCHEMBL24745467 | 0.82 | ALDH1A1 (0.37) | PKN1PKN2KDM4EALDH1A1MAPT | |
| SCHEMBL24745532 | 0.82 | DCTPP1 (0.38) | KDM4EALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115023419-A | Cereblon-bound piperidine-2, 6-diones and methods of use thereof | 凯普托尔治疗学股份有限公司 | 2022-09-06 | — | — | CN | disclosed |