Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 9/20 | 0.52 |
| ▸ | LOX | P28300 | 4/20 | 0.52 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4935143 | 1.00 | LOXL2 (0.52) | LOXL2LOXIKBKETBK1LOXL3 | |
| SCHEMBL4936674 | 0.92 | LOXL2 (0.50) | LOXL2LOXIKBKETBK1IRAK4 | |
| SCHEMBL4932984 | 0.81 | LOXL2 (0.74) | LOXL2LOXIKBKETBK1LOXL3 | |
| SCHEMBL429671 | 0.81 | LOXL2 (0.51) | LOXL2LOXLOXL3 | |
| SCHEMBL30578250 | 0.81 | LOXL2 (0.51) | LOXL2LOXLOXL3 | |
| SCHEMBL8277614 | 0.79 | GRM4 (0.42) | DHFRDCPSIRAK4TLR7GRM4 | |
| SCHEMBL15716837 | 0.79 | CCNA2 (0.43) | DHFRDCPSIRAK4EP300GRM4 | |
| SCHEMBL30931670 | 0.77 | LOXL2 (0.50) | LOXL2LOXLOXL3 | |
| SCHEMBL4937792 | 0.77 | XDH (0.41) | DHFRDCPSIRAK4 | |
| SCHEMBL4935204 | 0.76 | LOXL2 (0.66) | LOXL2LOXIKBKETBK1LOXL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630404-A1 | UREA COMPOUNDS AS ACTIVATORS OF POTASSIUM CHANNELS KV7.2/7.3 USEFUL IN THE TREATMENT OF CNS AND PNS DISORDERS | ANGELINI PHARMA S.P.A. (IT) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121048-A1 | UREA COMPOUNDS AS ACTIVATORS OF POTASSIUM CHANNELS KV7.2/7.3 USEFUL IN THE TREATMENT OF CNS AND PNS DISORDERS | ANGELINI PHARMA S.P.A. (IT) | 2024-06-13 | — | — | WO | disclosed |