SCHEMBL10042892

SCHEMBL10042892

CCCCc1ccc(N(c2ccccc2)c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.57
RARB P10826 6/20 0.53
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 1/20 0.46
RARA P10276 1/20 0.46
MAPT P10636 1/20 0.46
MTOR P42345 1/20 0.46
KMT2A Q03164 1/20 0.46
KCNH2 Q12809 2/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CHRM2 P08172 1/20 0.46
HTR1A P08908 1/20 0.46
ADRA2A P08913 1/20 0.46
CHRM1 P11229 1/20 0.46
DRD1 P21728 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
ADRA1A P35348 1/20 0.46
OPRM1 P35372 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12533891 0.98 RARB (0.54) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL11887113 0.98 HSD11B1 (0.58) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL289833 0.98 RARB (0.54) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL38667 0.98 RARB (0.54) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL309398 0.98 RARB (0.54) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL13474962 0.98 RARB (0.54) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL10042894 0.98 HSD11B1 (0.58) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL12386345 0.98 HSD11B1 (0.58) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL10042907 0.95 HSD11B1 (0.53) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL16234053 0.93 RARB (0.50) HSD11B1RARBALDH1A1MEN1RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120037889-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE AND ILLUMINATION DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2012-02-16 US disclosed