Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16097660 | 1.00 | ABCB1 (0.39) | ABCB1HASPINDYRK1AKITPDGFRA | |
| SCHEMBL19458891 | 0.85 | DYRK1A (0.53) | HASPINDYRK1A | |
| SCHEMBL30939919 | 0.85 | DYRK1A (0.53) | HASPINDYRK1A | |
| SCHEMBL30939972 | 0.84 | DYRK1A (0.47) | HASPINDYRK1AALDH1A1NQO2PDE5A | |
| SCHEMBL16123507 | 0.84 | DYRK1A (0.47) | HASPINDYRK1AALDH1A1NQO2PDE5A | |
| SCHEMBL30939902 | 0.82 | DYRK1A (0.55) | HASPINDYRK1A | |
| SCHEMBL16123596 | 0.82 | DYRK1A (0.55) | HASPINDYRK1A | |
| SCHEMBL16123600 | 0.80 | DYRK1A (0.38) | ABCB1HASPINDYRK1AGAAPDE5A | |
| SCHEMBL16123607 | 0.78 | XDH (0.38) | HASPINPDE5ASLC6A2SLC6A4 | |
| SCHEMBL16123621 | 0.78 | ABCB1 (0.42) | ABCB1HASPINALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113416187-B | Alkylamine harmine derivatives for promoting bone growth | 奥斯菲治疗有限公司 | 2024-07-19 | — | — | CN | disclosed |