Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.40 |
| ▸ | WEE1 | P30291 | 3/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16123507 | 1.00 | DYRK1A (0.47) | DYRK1AHTR2AHTR2CHASPINWEE1 | |
| SCHEMBL16123600 | 0.89 | DYRK1A (0.38) | DYRK1AHTR2AHTR2CHASPINPDE5A | |
| SCHEMBL16097660 | 0.84 | ABCB1 (0.39) | DYRK1AHASPINPDE5ANQO2ALDH1A1 | |
| SCHEMBL30939901 | 0.84 | ABCB1 (0.39) | DYRK1AHASPINPDE5ANQO2ALDH1A1 | |
| SCHEMBL16123510 | 0.84 | DYRK1A (0.69) | DYRK1AHTR2AHTR2CHASPIN | |
| SCHEMBL30939905 | 0.84 | DYRK1A (0.69) | DYRK1AHTR2AHTR2CHASPIN | |
| SCHEMBL16123581 | 0.81 | PER2 (0.34) | DYRK1AHTR2AHTR2CHASPINPDE5A | |
| SCHEMBL30939987 | 0.81 | PER2 (0.34) | DYRK1AHTR2AHTR2CHASPINPDE5A | |
| SCHEMBL30939988 | 0.81 | DYRK1A (0.71) | DYRK1AHTR2AHTR2CHASPIN | |
| SCHEMBL16123659 | 0.81 | DYRK1A (0.71) | DYRK1AHTR2AHTR2CHASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113416187-B | Alkylamine harmine derivatives for promoting bone growth | 奥斯菲治疗有限公司 | 2024-07-19 | — | — | CN | disclosed |