Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.38 |
| ▸ | WEE1 | P30291 | 3/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16123621 | 1.00 | ABCB1 (0.42) | ABCB1CNR2CHEK1WEE1SRC | |
| SCHEMBL16123622 | 0.98 | ABCB1 (0.42) | ABCB1CNR2CHEK1WEE1SRC | |
| SCHEMBL30940006 | 0.98 | ABCB1 (0.42) | ABCB1CNR2CHEK1WEE1SRC | |
| SCHEMBL30939870 | 0.95 | CNR2 (0.41) | CNR2HSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL16123513 | 0.95 | CNR2 (0.41) | CNR2HSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL30940002 | 0.88 | XDH (0.38) | WEE1HASPIN | |
| SCHEMBL16123607 | 0.88 | XDH (0.38) | WEE1HASPIN | |
| SCHEMBL30939991 | 0.86 | CCNE2 (0.52) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL16123624 | 0.86 | CCNE2 (0.52) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL16123658 | 0.85 | POLB (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113416187-B | Alkylamine harmine derivatives for promoting bone growth | 奥斯菲治疗有限公司 | 2024-07-19 | — | — | CN | disclosed |