Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 2/20 | 0.35 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | KIF5B | P33176 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16123607 | 1.00 | XDH (0.38) | XDHSLC6A2SLC6A4KCNH2HASPIN | |
| SCHEMBL30939951 | 0.94 | SLC6A2 (0.39) | XDHSLC6A2SLC6A4KCNH2HASPIN | |
| SCHEMBL16123589 | 0.94 | SLC6A2 (0.39) | XDHSLC6A2SLC6A4KCNH2HASPIN | |
| SCHEMBL30939996 | 0.88 | ABCB1 (0.42) | HASPINWEE1 | |
| SCHEMBL16123621 | 0.88 | ABCB1 (0.42) | HASPINWEE1 | |
| SCHEMBL30939946 | 0.86 | DYRK1A (0.48) | HASPIN | |
| SCHEMBL16123608 | 0.86 | DYRK1A (0.48) | HASPIN | |
| SCHEMBL30940006 | 0.86 | ABCB1 (0.42) | HASPINESR1ESR2WEE1 | |
| SCHEMBL16123622 | 0.86 | ABCB1 (0.42) | HASPINESR1ESR2WEE1 | |
| SCHEMBL16123663 | 0.83 | DYRK1A (0.49) | HASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113416187-B | Alkylamine harmine derivatives for promoting bone growth | 奥斯菲治疗有限公司 | 2024-07-19 | — | — | CN | disclosed |