Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202659 | 0.86 | MGLL (0.56) | MGLLCHRNA7CTSDOPRK1OPRM1 | |
| SCHEMBL8202651 | 0.86 | MGLL (0.56) | MGLLCHRNA7CTSDOPRK1OPRM1 | |
| SCHEMBL4500495 | 0.84 | MGLL (0.60) | MGLLCHRNA7CTSDOPRK1OPRM1 | |
| SCHEMBL4523787 | 0.81 | MGLL (0.58) | MGLLCHRNA7CTSDOPRK1OPRM1 | |
| SCHEMBL7373733 | 0.81 | MGLL (0.53) | MGLLCHRNA7OPRK1OPRM1OPRL1 | |
| SCHEMBL12450875 | 0.81 | ALDH1A1 (0.56) | MGLLCHRNA7OPRK1OPRM1OPRL1 | |
| SCHEMBL4525994 | 0.79 | MGLL (0.62) | MGLLCHRNA7OPRK1OPRM1OPRL1 | |
| SCHEMBL4526146 | 0.79 | MGLL (0.62) | MGLLCHRNA7OPRK1OPRM1OPRL1 | |
| SCHEMBL4505498 | 0.79 | MGLL (0.62) | MGLLCHRNA7OPRK1OPRM1OPRL1 | |
| SCHEMBL484801 | 0.78 | CRBN (0.57) | CHRNA7CTSDOPRK1OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359631-A | Polycyclic PI3K alpha inhibitors | 轩竹生物科技股份有限公司 | 2024-07-19 | — | — | CN | disclosed |