Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.46 |
| ▸ | JAK1 | P23458 | 8/20 | 0.44 |
| ▸ | JAK2 | O60674 | 6/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | KIT | P10721 | 3/20 | 0.35 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940499 | 0.89 | TYK2 (0.44) | TYK2JAK1JAK2JAK3STAT3 | |
| SCHEMBL30940500 | 0.87 | TYK2 (0.36) | TYK2JAK1JAK2JAK3KCNH2 | |
| SCHEMBL20985231 | 0.84 | TYK2 (0.63) | TYK2JAK1JAK2JAK3STAT3 | |
| SCHEMBL30940516 | 0.83 | TYK2 (0.42) | TYK2JAK1JAK2JAK3STAT3 | |
| SCHEMBL30617361 | 0.76 | TYK2 (0.40) | TYK2JAK1JAK2JAK3STAT3 | |
| SCHEMBL30940517 | 0.74 | TYK2 (0.53) | TYK2JAK1JAK2JAK3STAT3 | |
| SCHEMBL30068348 | 0.74 | TYK2 (0.46) | TYK2JAK1JAK2JAK3STAT3 | |
| SCHEMBL20985239 | 0.73 | TYK2 (0.79) | TYK2JAK1JAK2JAK3STAT3 | |
| SCHEMBL30617390 | 0.73 | TYK2 (0.79) | TYK2JAK1JAK2JAK3STAT3 | |
| SCHEMBL30940487 | 0.72 | TYK2 (0.39) | TYK2JAK1JAK2JAK3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315737-B | Heteroaryl compounds substituted with sulfone pyridinylalkylamides | 百时美施贵宝公司 | 2024-06-18 | — | — | CN | disclosed |