SCHEMBL30940772

SCHEMBL30940772

CC(C)(C)OC(=O)N1CCC([C@H]2C[C@@H](n3cc4c5c(ncnc53)NCCC4)[C@@H]3OC(C)(C)O[C@@H]32)CC1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 10/20 0.36
▸ SRC P12931 5/20 0.35
▸ EGFR P00533 3/20 0.35
▸ ITGAV P06756 2/20 0.34
▸ ITGB6 P18564 2/20 0.34
▸ ABL1 P00519 2/20 0.33
▸ ABL2 P42684 2/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ FAAH O00519 1/20 0.32
▸ PIK3CD O00329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25046657 1.00 GPR119 (0.36) GPR119SRCEGFRITGAVITGB6
SCHEMBL25046659 0.81 SRC (0.44) GPR119SRCEGFRITGAVITGB6
SCHEMBL25047935 0.80 SRC (0.37) GPR119SRCEGFRABL1ABL2
SCHEMBL25047540 0.80 SRC (0.45) SRCEGFRABL1ABL2RAB9A
SCHEMBL30941058 0.80 SRC (0.45) SRCEGFRABL1ABL2RAB9A
SCHEMBL31617969 0.77 ITGAV (0.31) ITGAVITGB6
SCHEMBL31617907 0.77 — —
SCHEMBL25047680 0.77 — —
SCHEMBL31617984 0.77 ADORA3 (0.30) —
SCHEMBL31617972 0.76 SRC (0.39) GPR119SRCEGFRABL1ABL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188110-A1 SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2025-06-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188110-A1 SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION KMT5A, KMT5B, KMT5C GPR119 1497/4885SRC 968/4885EGFR 1687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback