Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 6/20 | 0.48 |
| ▸ | MAOA | P21397 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4207937 | 1.00 | PTGDR2 (0.51) | PTGDR2MAOBMAOACYP3A4TSHR | |
| SCHEMBL6049299 | 0.87 | PTGDR2 (0.44) | PTGDR2CYP3A4TSHRCYP2D6CYP2C19 | |
| SCHEMBL3328668 | 0.87 | PTGDR2 (0.68) | PTGDR2MAOBMAOACYP3A4TSHR | |
| SCHEMBL18412824 | 0.86 | PTGDR2 (0.50) | PTGDR2MAOBMAOATSHRHTT | |
| SCHEMBL21046515 | 0.86 | TDP1 (0.47) | PTGDR2CYP3A4TSHRCYP2D6CYP2C19 | |
| SCHEMBL89047 | 0.84 | PTGDR2 (0.49) | PTGDR2MAOBMAOAHTTMAPT | |
| SCHEMBL20505374 | 0.83 | TSHR (0.61) | PTGDR2MAOBMAOACYP3A4TSHR | |
| SCHEMBL31088170 | 0.83 | KDM4E (0.49) | MAOBMAOACYP3A4TSHRCYP2D6 | |
| SCHEMBL5445458 | 0.83 | KDM4E (0.49) | MAOBMAOACYP3A4TSHRCYP2D6 | |
| SCHEMBL4215199 | 0.82 | ALDH1A1 (0.57) | CYP3A4TSHRCYP2D6CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522154-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |