Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 11/20 | 0.75 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320431 | 1.00 | NAMPT (0.75) | NAMPTRAB9ATP53MAPTNPC1 | |
| SCHEMBL23320381 | 0.86 | NAMPT (1.00) | NAMPTRAB9AMAPTNPC1HTT | |
| SCHEMBL23320510 | 0.78 | NAMPT (0.71) | NAMPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL23320437 | 0.78 | NAMPT (0.65) | NAMPTRAB9AHTTALDH1A1 | |
| SCHEMBL23320408 | 0.78 | NAMPT (0.84) | NAMPTRAB9ATP53MAPTNPC1 | |
| SCHEMBL23320402 | 0.76 | NAMPT (0.81) | NAMPTRAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL3207366 | 0.75 | MAPT (0.55) | RAB9ATP53MAPTNPC1ALDH1A1 | |
| SCHEMBL11713731 | 0.72 | IMPDH2 (0.74) | NAMPTRAB9AHTTALDH1A1IMPDH2 | |
| SCHEMBL27188684 | 0.72 | MAPT (0.75) | RAB9ATP53MAPTNPC1ALDH1A1 | |
| SCHEMBL14626708 | 0.71 | TP53 (0.53) | RAB9ATP53MAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |