SCHEMBL30943804

SCHEMBL30943804

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN)C(=O)N[C@H](C(=O)O)C(C)C

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CTSD P07339 8/20 0.40
CTSB P07858 1/20 0.40
SLC15A2 Q16348 1/20 0.39
BACE1 P56817 1/20 0.39
REN P00797 3/20 0.38
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38
GRPR P30550 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29720798 0.91 SLC15A2 (0.42) SLC15A2REN
SCHEMBL6381992 0.91 SLC15A2 (0.44) SLC15A2RENOPRM1OPRD1
SCHEMBL31443168 0.89 CTSD (0.40) CTSDCTSBSLC15A2RENGRPR
SCHEMBL27624894 0.88 REN (0.44) SLC15A2RENGRPR
SCHEMBL28520373 0.86 PSMB5 (0.46) CTSDCTSBREN
SCHEMBL29881596 0.85 BACE1 (0.46) CTSDBACE1OPRM1OPRD1
SCHEMBL5529308 0.85 SLC15A2 (0.39) SLC15A2REN
SCHEMBL29757203 0.84 SLC15A2 (0.37) CTSDSLC15A2BACE1RENOPRD1
SCHEMBL29590566 0.84 SLC15A2 (0.49) SLC15A2
SCHEMBL20783813 0.84 SLC15A2 (0.49) SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119060138-B Targeting Nectin-4 cyclic peptide and preparation method and application thereof 上海美迪西生物医药股份有限公司 2025-02-11 CN disclosed
CN-119060138-A Targeting Nectin-4 cyclic peptide and preparation method and application thereof 上海美迪西生物医药股份有限公司 2024-12-03 CN disclosed
CN-117986367-B Antibody with target as Nectin-4 and application thereof 上海美迪西生物医药股份有限公司 2024-07-16 CN disclosed
CN-118146373-A Single B cell antibody and application thereof 上海美迪西生物医药股份有限公司 2024-06-07 CN disclosed
CN-117986367-A Antibody with target as Nectin-4 and application thereof 上海美迪西生物医药股份有限公司 2024-05-07 CN disclosed