Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 10/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 10/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 9/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 9/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28512789 | 1.00 | DYRK1A (0.58) | DYRK1AFSCN1CASP3SENP7SENP8 | |
| SCHEMBL30944291 | 0.87 | ADORA1 (0.58) | DYRK1ACYP2D6CYP2B6CYP2C19NPC1 | |
| SCHEMBL28530522 | 0.87 | ADORA1 (0.58) | DYRK1ACYP2D6CYP2B6CYP2C19NPC1 | |
| SCHEMBL30944383 | 0.85 | DYRK1A (0.56) | DYRK1AFSCN1CASP3SENP7SENP8 | |
| SCHEMBL30944285 | 0.84 | DYRK1A (0.60) | DYRK1ACYP2D6NPC1RAB9A | |
| SCHEMBL28530536 | 0.84 | DYRK1A (0.60) | DYRK1ACYP2D6NPC1RAB9A | |
| SCHEMBL30944289 | 0.83 | NPC1 (0.49) | DYRK1ACYP2C19NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28522084 | 0.83 | NPC1 (0.49) | DYRK1ACYP2C19NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30944352 | 0.82 | DYRK1A (0.63) | DYRK1AFSCN1CASP3SENP7SENP8 | |
| SCHEMBL30944353 | 0.82 | CNR1 (0.70) | DYRK1AFSCN1CASP3SENP7SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3758697-B1 | NOVEL ANTIMYCOBACTERIAL HETEROCYCLIC AMIDES | CRESTONE INC (US) | 2024-10-16 | — | — | EP | claimed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |