Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.63 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 10/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 10/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 9/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 9/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CLK1 | P49759 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944341 | 0.86 | ADORA1 (0.80) | DYRK1AADORA1CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL28518062 | 0.83 | DYRK1A (0.65) | DYRK1AADORA1CYP2D6 | |
| SCHEMBL30944303 | 0.83 | DYRK1A (0.65) | DYRK1AADORA1CYP2D6 | |
| SCHEMBL31236382 | 0.83 | DYRK1A (0.65) | DYRK1AADORA1CYP2D6 | |
| SCHEMBL28527314 | 0.83 | DYRK1A (0.65) | DYRK1AADORA1CYP2D6 | |
| SCHEMBL30944286 | 0.82 | DYRK1A (0.58) | DYRK1AFSCN1CASP3SENP7SENP8 | |
| SCHEMBL28512789 | 0.82 | DYRK1A (0.58) | DYRK1AFSCN1CASP3SENP7SENP8 | |
| SCHEMBL30944362 | 0.81 | DYRK1A (0.67) | DYRK1AADORA1CYP2D6 | |
| SCHEMBL28519830 | 0.81 | DYRK1A (0.67) | DYRK1AADORA1CYP2D6 | |
| SCHEMBL30944305 | 0.81 | ADORA1 (0.57) | DYRK1AADORA1CYP2C19LCKNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |