Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.71 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28529051 | 1.00 | ADORA1 (0.71) | ADORA1DYRK1ARAB9ANPC1HTT | |
| SCHEMBL30944291 | 0.91 | ADORA1 (0.58) | ADORA1DYRK1ARAB9ANPC1HTT | |
| SCHEMBL28530522 | 0.91 | ADORA1 (0.58) | ADORA1DYRK1ARAB9ANPC1HTT | |
| SCHEMBL30944415 | 0.85 | ADORA1 (0.62) | ADORA1DYRK1ARAB9ANPC1HTT | |
| SCHEMBL30944376 | 0.83 | ADORA1 (1.00) | ADORA1DYRK1ARAB9ANPC1HTT | |
| SCHEMBL30944373 | 0.82 | ADORA1 (0.98) | ADORA1DYRK1ARAB9ANPC1HTT | |
| SCHEMBL30944286 | 0.80 | DYRK1A (0.58) | DYRK1ARAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL28512789 | 0.80 | DYRK1A (0.58) | DYRK1ARAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL30944285 | 0.78 | DYRK1A (0.60) | DYRK1ARAB9ANPC1CYP2D6 | |
| SCHEMBL28530536 | 0.78 | DYRK1A (0.60) | DYRK1ARAB9ANPC1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3758697-B1 | NOVEL ANTIMYCOBACTERIAL HETEROCYCLIC AMIDES | CRESTONE INC (US) | 2024-10-16 | — | — | EP | claimed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |