Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944373 | 0.99 | ADORA1 (0.98) | ADORA1DYRK1ARAB9ANPC1HTT | |
| SCHEMBL30944341 | 0.89 | ADORA1 (0.80) | ADORA1DYRK1ARAB9ANPC1HTT | |
| SCHEMBL30944288 | 0.83 | ADORA1 (0.71) | ADORA1DYRK1ARAB9ANPC1HTT | |
| SCHEMBL28529051 | 0.83 | ADORA1 (0.71) | ADORA1DYRK1ARAB9ANPC1HTT | |
| SCHEMBL856499 | 0.79 | DYRK1A (1.00) | ADORA1DYRK1ARAB9ANPC1HTT | |
| SCHEMBL12502694 | 0.77 | DYRK1A (0.76) | ADORA1DYRK1ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30944352 | 0.77 | DYRK1A (0.63) | ADORA1DYRK1ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30944415 | 0.77 | ADORA1 (0.62) | ADORA1DYRK1ARAB9ANPC1HTT | |
| SCHEMBL18850998 | 0.76 | DYRK1A (0.69) | ADORA1DYRK1ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30944362 | 0.75 | DYRK1A (0.67) | ADORA1DYRK1ACYP2D6ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |