Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.58 |
| ▸ | NCS1 | P62166 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520781 | 1.00 | DYRK1A (0.58) | DYRK1ANCS1CNR1CYP2D6NPC1 | |
| SCHEMBL28530647 | 0.92 | DYRK1A (0.58) | DYRK1ACNR1CYP2D6NPC1RAB9A | |
| SCHEMBL30944301 | 0.92 | DYRK1A (0.58) | DYRK1ACNR1CYP2D6NPC1RAB9A | |
| SCHEMBL30944318 | 0.92 | DYRK1A (0.58) | DYRK1ACNR1CYP2D6NPC1RAB9A | |
| SCHEMBL30944406 | 0.87 | DYRK1A (0.56) | DYRK1ACNR1NPC1RAB9ACSNK1D | |
| SCHEMBL30944415 | 0.85 | ADORA1 (0.62) | DYRK1ACNR1CYP2D6NPC1RAB9A | |
| SCHEMBL30944351 | 0.85 | CNR1 (0.51) | DYRK1ACNR1CYP2D6NPC1RAB9A | |
| SCHEMBL30944407 | 0.83 | NPC1 (0.50) | CNR1NPC1RAB9ACSNK1DADORA1 | |
| SCHEMBL30944393 | 0.82 | CNR1 (0.71) | DYRK1ACNR1NPC1RAB9ACSNK1D | |
| SCHEMBL31236381 | 0.81 | NPC1 (0.66) | DYRK1ACNR1NPC1RAB9AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |