Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31236381 | 0.87 | NPC1 (0.66) | NPC1RAB9ACNR1GAAHTT | |
| SCHEMBL30944406 | 0.87 | DYRK1A (0.56) | NPC1RAB9ACNR1ALOX15GAA | |
| SCHEMBL28530631 | 0.84 | DYRK1A (0.55) | NPC1RAB9ACNR1HTTCLK1 | |
| SCHEMBL30944384 | 0.84 | DYRK1A (0.55) | NPC1RAB9ACNR1HTTCLK1 | |
| SCHEMBL30944410 | 0.84 | GAA (0.47) | NPC1RAB9ACNR1ALOX15GAA | |
| SCHEMBL30944383 | 0.83 | DYRK1A (0.56) | NPC1RAB9ACNR1CLK1KMT2A | |
| SCHEMBL30944415 | 0.83 | ADORA1 (0.62) | NPC1RAB9ACNR1ALOX15GAA | |
| SCHEMBL30944300 | 0.83 | RAB9A (0.56) | NPC1RAB9ACNR1ALOX15GAA | |
| SCHEMBL30944419 | 0.83 | RAB9A (0.56) | NPC1RAB9ACNR1GAAHTT | |
| SCHEMBL30944351 | 0.83 | CNR1 (0.51) | NPC1RAB9ACNR1ALOX15GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |