Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 10/20 | 0.66 |
| ▸ | RAB9A | P51151 | 9/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | CLK1 | P49759 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530651 | 1.00 | MAOA (0.67) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28519839 | 1.00 | MAOA (0.67) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30944367 | 1.00 | MAOA (0.67) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28908448 | 0.88 | DYRK1A (0.68) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28525158 | 0.88 | DYRK1A (0.68) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30944330 | 0.88 | DYRK1A (0.68) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30944348 | 0.88 | DYRK1A (0.68) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30944381 | 0.87 | MAOA (0.51) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28520783 | 0.87 | MAOA (0.51) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL18154343 | 0.87 | DYRK1A (0.67) | MAOAMAOBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |