SCHEMBL30944751

SCHEMBL30944751

CCOC(=O)/C=C/c1ccc(CNC(=O)OC(C)(C)C)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.55
CA1 P00915 2/20 0.55
CA7 P43166 2/20 0.55
CA9 Q16790 2/20 0.55
CA14 Q9ULX7 2/20 0.55
CA2 P00918 1/20 0.55
CYP3A4 P08684 1/20 0.49
TTR P02766 1/20 0.48
DPP4 P27487 1/20 0.48
KDM4E B2RXH2 2/20 0.47
MAPT P10636 1/20 0.47
LMNA P02545 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
MAOB P27338 1/20 0.44
NAMPT P43490 2/20 0.43
FDPS P14324 1/20 0.43
GAA P10253 1/20 0.43
AKR1C3 P42330 1/20 0.42
PPIB P23284 1/20 0.42
PPIA P62937 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6987937 1.00 CA12 (0.55) CA12CA1CA7CA9CA14
SCHEMBL3674926 0.88 CA1 (0.51) CA12CA1CA7CA9CA14
SCHEMBL1165045 0.88 CA1 (0.51) CA12CA1CA7CA9CA14
SCHEMBL4087563 0.88 CA12 (0.56) CA12CA1CA7CA9CA14
SCHEMBL4087559 0.88 CA12 (0.56) CA12CA1CA7CA9CA14
SCHEMBL4491710 0.88 CA1 (0.52) CA12CA1CA7CA9CA14
SCHEMBL2174596 0.86 TTR (0.47) CA12CA1CA7CA9CA14
SCHEMBL2174598 0.86 TTR (0.47) CA12CA1CA7CA9CA14
SCHEMBL5598393 0.84 L3MBTL1 (0.48) CA12CA1CA7CA14CA2
SCHEMBL5598396 0.84 L3MBTL1 (0.48) CA12CA1CA7CA14CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4629984-A1 DEVELOPMENT OF POTENT DUAL HDAC/BRD4 INHIBITORS BioVentures, LLC (US) 2025-10-15 EP disclosed
WO-2024123929-A1 DEVELOPMENT OF POTENT DUAL HDAC/BRD4 INHIBITORS BIOVENTURES, LLC (US) 2024-06-13 WO disclosed