Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3674926 | 1.00 | CA1 (0.51) | CA1CA2CA12TYRCA7 | |
| SCHEMBL30944751 | 0.88 | CA12 (0.55) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6987937 | 0.88 | CA12 (0.55) | CA1CA2CA12CA7CA9 | |
| SCHEMBL5598393 | 0.88 | L3MBTL1 (0.48) | CA1CA2CA12CA7CA14 | |
| SCHEMBL5598396 | 0.88 | L3MBTL1 (0.48) | CA1CA2CA12CA7CA14 | |
| SCHEMBL27908341 | 0.86 | HDAC3 (0.56) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL3439467 | 0.85 | NR1H4 (0.49) | NR1H4KDM4EPTPN1TTRAPP | |
| SCHEMBL31389315 | 0.85 | NR1H4 (0.49) | NR1H4KDM4EPTPN1TTRAPP | |
| SCHEMBL1164581 | 0.85 | NR1H4 (0.49) | NR1H4KDM4EPTPN1TTRAPP | |
| SCHEMBL3180689 | 0.82 | L3MBTL1 (0.61) | CA1CA2CA12CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451790-A1 | HISTONE DEACETYLASE INHIBITORS | Anthem Biosciences Private Limited (IN) | 2012-05-16 | — | — | EP | disclosed |
| US-20120101099-A1 | HISTONE DEACETYLASE INHIBITORS | ANTHEM BIOSCIENCES PRIVATE LIMITED (IN) | 2012-04-26 | — | — | US | disclosed |
| WO-2011021209-A1 | HISTONE DEACETYLASE INHIBITORS | PORTSMOUTH TECHNOLOGIES LLC (US) | 2011-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101099-A1 | HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC3, HDAC11 | CA1 1036/4885CA2 2841/4885CA12 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.