Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | PLK1 | P53350 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998802 | 1.00 | DOT1L (0.65) | DOT1LHTTALOX15PLK1NPC1 | |
| Hydrochloric Acid SCHEMBL1879577 | 0.98 | DOT1L (0.63) | DOT1LHTTALOX15PLK1NPC1 | |
| SCHEMBL2524478 | 0.86 | ALDH1A1 (0.55) | DOT1LHTTALOX15PLK1NPC1 | |
| SCHEMBL27856105 | 0.85 | DOT1L (0.73) | DOT1LHTTALOX15PLK1NPC1 | |
| SCHEMBL29489054 | 0.84 | HTT (0.66) | DOT1LHTTALOX15PLK1NPC1 | |
| SCHEMBL323178 | 0.84 | HTT (0.66) | DOT1LHTTALOX15PLK1NPC1 | |
| SCHEMBL2976951 | 0.83 | HDAC1 (0.61) | DOT1LHTTALOX15PLK1NPC1 | |
| SCHEMBL24021437 | 0.82 | HTT (0.64) | DOT1LHTTALOX15PLK1NPC1 | |
| Hydrochloric Acid SCHEMBL998803 | 0.82 | HTT (0.64) | DOT1LHTTALOX15PLK1NPC1 | |
| SCHEMBL21169603 | 0.82 | DOT1L (0.65) | DOT1LHTTALOX15PLK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772139-A | Organic electroluminescent compounds and organic electroluminescent device thereof | 陶氏环球技术有限责任公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-114805337-B | Organic electroluminescent compounds and organic electroluminescent device thereof | 陶氏环球技术有限责任公司 | 2024-07-23 | — | — | CN | disclosed |