Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | PLK1 | P53350 | 1/20 | 0.66 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.62 |
| ▸ | MGAM | O43451 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29489054 | 1.00 | HTT (0.66) | HTTALOX15PLK1DOT1LMGAM | |
| Hydrochloric Acid SCHEMBL998803 | 0.98 | HTT (0.64) | HTTALOX15PLK1DOT1LMGAM | |
| Hydrochloric Acid SCHEMBL7309164 | 0.98 | HTT (0.64) | HTTALOX15PLK1DOT1LMGAM | |
| Quinoline SCHEMBL28071416 | 0.95 | MGAM (0.65) | HTTALOX15PLK1DOT1LMGAM | |
| SCHEMBL9102023 | 0.91 | ALDH1A1 (0.70) | HTTALOX15PLK1DOT1LMGAM | |
| SCHEMBL27462494 | 0.88 | ALOX15 (0.54) | HTTALOX15PLK1DOT1LMGAM | |
| SCHEMBL27856105 | 0.87 | DOT1L (0.73) | HTTALOX15PLK1DOT1LALDH1A1 | |
| Isoquinoline SCHEMBL28207937 | 0.87 | MGAM (0.55) | HTTALOX15PLK1DOT1LMGAM | |
| Imidazole SCHEMBL8706168 | 0.85 | ALOX15 (0.51) | HTTALOX15PLK1DOT1LMGAM | |
| SCHEMBL29406417 | 0.85 | ALDH1A1 (0.56) | HTTALOX15PLK1MGAMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1611 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118497918-B | Preparation method and application of lyocell fiber containing chlorella component | 华东理工大学 | 2024-11-15 | — | — | CN | claimed |
| EP-4182308-B1 | PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARM SPA (IT) | 2024-09-04 | — | — | EP | claimed |
| CN-118497918-A | Preparation method and application of lyocell fiber containing chlorella component | 华东理工大学 | 2024-08-16 | — | — | CN | claimed |
| CN-118104533-B | Seedling raising method for improving saline-alkali tolerance of watermelon seedlings | 优奈尔生物科技有限公司 | 2024-08-06 | — | — | CN | claimed |
| CN-118104533-A | Seedling raising method for improving saline-alkali tolerance of watermelon seedlings | 优奈尔生物科技有限公司 | 2024-05-31 | — | — | CN | claimed |
| US-11884647-B2 | Compounds and methods for targeting pathogenic blood vessels | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-01-30 | — | — | US | claimed |
| CN-117244479-A | Preparation system and method of high-purity m-methylbenzoic acid | 上海元革新材料科技有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-117088915-A | Preparation method and application of 6-quinolinic acid coordinated metal catalyst and compound | 上海元革新材料科技有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-116813919-A | Copper-based metal organic framework material and preparation method and application thereof | 江苏科技大学 | 2023-09-29 | — | — | CN | claimed |
| CN-111138477-B | Preparation method and application of tricyclohexyltin quinoline-6-formate complex | 衡阳师范学院 | 2023-06-23 | — | — | CN | claimed |
| EP-0730597-B1 | HETEROCYCLIC ESTERS OF RAPAMYCIN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN HOME PROD (US) | 2001-03-07 | — | — | EP | claimed |
| EP-1037878-A2 | METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES | NPS PHARMACEUTICALS, INC. (US) | 2000-09-27 | — | — | EP | claimed |
| WO-2000034260-A2 | ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | claimed |
| WO-1999026927-A2 | METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES | NPS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | claimed |
| US-5852190-A | Diazepinoindoles as phosphodiesterase IV inhibitors | INSTITUT DE RECHERCHE JOUVEINAL SA (FR) | 1998-12-22 | — | — | US | claimed |
| CN-1157611-A | Novel quinolone 5- (N-heterosubstituted amino) antimicrobial agents | PROCTER & GAMBLE (US) | 1997-08-20 | — | — | CN | claimed |
| EP-0730597-A1 | HETEROCYCLIC ESTERS OF RAPAMYCIN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-11 | — | — | EP | claimed |
| WO-1995014697-A1 | HETEROCYCLIC ESTERS OF RAPAMYCIN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-06-01 | — | — | WO | claimed |
| EP-0639570-A1 | Process for the preparation of aromatic carboxylic acids | BASF Aktiengesellschaft (DE) | 1995-02-22 | — | — | EP | claimed |
| US-5385909-A | Heterocyclic esters of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-01-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884647-B2 | Compounds and methods for targeting pathogenic blood vessels | TEK, KDR, LIPG | HTT 2091/4885ALOX15 1739/4885PLK1 657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.