Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29230131 | 1.00 | MAPT (0.54) | MAPTKDM4EPOLBRAD52MEN1 | |
| SCHEMBL29230157 | 0.93 | POLB (0.56) | MAPTKDM4EPOLBRAD52MEN1 | |
| SCHEMBL30944961 | 0.93 | POLB (0.56) | MAPTKDM4EPOLBRAD52MEN1 | |
| SCHEMBL29230169 | 0.89 | MAPT (0.52) | MAPTKDM4EPOLBRAD52MEN1 | |
| SCHEMBL30944992 | 0.89 | MAPT (0.52) | MAPTKDM4EPOLBRAD52MEN1 | |
| SCHEMBL30945026 | 0.89 | MEN1 (0.59) | MAPTKDM4EPOLBRAD52MEN1 | |
| SCHEMBL29230128 | 0.89 | MEN1 (0.59) | MAPTKDM4EPOLBRAD52MEN1 | |
| Hydrochloric Acid SCHEMBL30945011 | 0.87 | MEN1 (0.48) | MAPTKDM4EPOLBRAD52MEN1 | |
| Hydrochloric Acid SCHEMBL29230274 | 0.87 | MEN1 (0.48) | MAPTKDM4EPOLBRAD52MEN1 | |
| SCHEMBL30945007 | 0.86 | SLC2A1 (0.54) | MAPTKDM4EPOLBRAD52MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146151-A | 4-Trifluoromethyl substituted quinoline and quinazoline compound and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2024-06-07 | — | — | CN | disclosed |