Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21381761 | 0.98 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7956279 | 0.84 | SLC6A3 (0.58) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL10963570 | 0.83 | SLC6A3 (0.43) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL16657609 | 0.83 | SLC6A3 (0.52) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL8191324 | 0.83 | CHRNB4 (0.46) | SLC6A3SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL2586181 | 0.81 | CHRNB4 (0.45) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7319671 | 0.77 | SLC6A2 (0.45) | SLC6A3SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9768345 | 0.75 | SLC6A2 (0.46) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL8309312 | 0.74 | SLC6A2 (0.58) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3591892 | 0.74 | RPS6KB1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199587-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199587-A1 | HETEROCYCLIC COMPOUNDS | CYP1B1, CYP1A1, CYP4B1 | SLC6A3 4328/4885SLC6A2 4429/4885SLC6A4 4134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.