Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.52 |
| ▸ | KISS1R | Q969F8 | 9/20 | 0.52 |
| ▸ | NPY1R | P25929 | 3/20 | 0.51 |
| ▸ | NPY2R | P49146 | 3/20 | 0.51 |
| ▸ | NPY4R | P50391 | 3/20 | 0.51 |
| ▸ | GHSR | Q92847 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 2/20 | 0.48 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29732610 | 0.98 | KISS1R (0.54) | MAGI3KISS1RNPY1RNPY2RNPY4R | |
| SCHEMBL31110538 | 0.98 | KISS1R (0.54) | MAGI3KISS1RNPY1RNPY2RNPY4R | |
| SCHEMBL30339696 | 0.98 | KISS1R (0.54) | MAGI3KISS1RNPY1RNPY2RNPY4R | |
| SCHEMBL30302874 | 0.98 | KISS1R (0.54) | MAGI3KISS1RNPY1RNPY2RNPY4R | |
| SCHEMBL30305295 | 0.98 | KISS1R (0.54) | MAGI3KISS1RNPY1RNPY2RNPY4R | |
| SCHEMBL30148460 | 0.98 | KISS1R (0.54) | MAGI3KISS1RNPY1RNPY2RNPY4R | |
| SCHEMBL29800092 | 0.98 | KISS1R (0.54) | MAGI3KISS1RNPY1RNPY2RNPY4R | |
| SCHEMBL30945347 | 0.98 | MAGI3 (0.52) | MAGI3KISS1RNPY1RNPY2RNPY4R | |
| SCHEMBL30093131 | 0.97 | MAGI3 (0.52) | MAGI3KISS1RNPY1RNPY2RNPY4R | |
| SCHEMBL29379367 | 0.96 | GHSR (0.55) | GHSRIL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373885-A | Indole derivative and synthesis method and application thereof | 德州学院 | 2024-07-23 | — | — | CN | claimed |
| CN-118373885-B | Indole derivative and synthesis method and application thereof | 德州学院 | 2024-11-01 | — | — | CN | disclosed |
| CN-118373885-A | Indole derivative and synthesis method and application thereof | 德州学院 | 2024-07-23 | — | — | CN | disclosed |