Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 10/20 | 0.52 |
| ▸ | RAB9A | P51151 | 10/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30945519 | 0.86 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ADORA1DYRK1A | |
| SCHEMBL30945498 | 0.85 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ADORA1DYRK1A | |
| SCHEMBL30945507 | 0.84 | RAB9A (0.51) | NPC1RAB9ASMN1; SMN2ADORA1DYRK1A | |
| SCHEMBL30945533 | 0.84 | RAB9A (0.57) | NPC1RAB9ASMN1; SMN2ADORA1DYRK1A | |
| SCHEMBL30945528 | 0.84 | GAA (0.50) | NPC1RAB9ASMN1; SMN2ADORA1DYRK1A | |
| SCHEMBL880239 | 0.84 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2ADORA1DYRK1A | |
| SCHEMBL13522380 | 0.84 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2ADORA1DYRK1A | |
| SCHEMBL30945512 | 0.83 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2ADORA1DYRK1A | |
| SCHEMBL6905520 | 0.82 | NPC1 (0.67) | BUB1NPC1RAB9ASMN1; SMN2ADORA1 | |
| SCHEMBL30945492 | 0.81 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2ADORA1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638427-A1 | AMIDINOUREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER | Université Côte d'Azur (FR) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024133857-A1 | AMIDINOUREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER | UNIVERSITE COTE D'AZUR (FR) | 2024-06-27 | — | — | WO | disclosed |