Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.57 |
| ▸ | NPC1 | O15118 | 11/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.53 |
| ▸ | RELA | Q04206 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30945507 | 0.86 | RAB9A (0.51) | RAB9ANPC1KDM4ENFKB1NFKB2 | |
| SCHEMBL30945519 | 0.86 | NPC1 (0.55) | RAB9ANPC1POLBKDM4ENFKB1 | |
| SCHEMBL30945528 | 0.86 | GAA (0.50) | RAB9ANPC1POLBKDM4ENFKB1 | |
| SCHEMBL30945503 | 0.85 | RAB9A (0.62) | RAB9ANPC1POLBKDM4ENFKB1 | |
| SCHEMBL30945514 | 0.84 | BUB1 (0.53) | RAB9ANPC1POLBKDM4ENFKB1 | |
| SCHEMBL30945512 | 0.83 | NPC1 (0.58) | RAB9ANPC1POLBKDM4ENFKB1 | |
| SCHEMBL30945492 | 0.83 | NPC1 (0.58) | RAB9ANPC1POLBKDM4ENFKB1 | |
| SCHEMBL11421487 | 0.81 | RAB9A (0.77) | RAB9ANPC1POLBKDM4ENFKB1 | |
| SCHEMBL30945498 | 0.81 | NPC1 (0.53) | RAB9ANPC1KDM4ENFKB1NFKB2 | |
| SCHEMBL30945490 | 0.80 | DHODH (0.59) | RAB9ANPC1POLBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638427-A1 | AMIDINOUREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER | Université Côte d'Azur (FR) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024133857-A1 | AMIDINOUREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER | UNIVERSITE COTE D'AZUR (FR) | 2024-06-27 | — | — | WO | disclosed |