Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27246689 | 0.82 | TDP1 (0.52) | DRD2TDP1MAOAMAOBCA12 | |
| SCHEMBL1308684 | 0.81 | DRD2 (0.55) | DRD2TDP1MAOAMAOB | |
| SCHEMBL27246709 | 0.79 | MEN1 (0.49) | DRD2CA12CA2CA9 | |
| SCHEMBL3387585 | 0.76 | DRD2 (0.47) | DRD2TDP1CAMK2D | |
| SCHEMBL6675697 | 0.75 | DRD2 (0.46) | DRD2TDP1MAOAMAOBCA12 | |
| SCHEMBL24618412 | 0.74 | DRD2 (0.48) | DRD2TDP1CAMK2D | |
| SCHEMBL18918073 | 0.74 | CYP2A6 (0.43) | DRD2TDP1PIM1PIM3 | |
| SCHEMBL24618706 | 0.74 | DRD2 (0.43) | DRD2TDP1CA12CA1CA2 | |
| SCHEMBL30945672 | 0.73 | CYP3A4 (0.50) | DRD2TDP1CACNA1GCYP3A4 | |
| SCHEMBL3388119 | 0.73 | DRD2 (0.44) | DRD2TDP1CAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | DCAF1, DDB1, CUL4A | DRD2 4684/4885TDP1 797/4885PIM1 1490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.