Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387585 | 0.79 | DRD2 (0.47) | DRD2TDP1CAMK2DSIGMAR1MEN1 | |
| SCHEMBL24618706 | 0.77 | DRD2 (0.43) | DRD2CA1CA2CA12CA9 | |
| SCHEMBL3388119 | 0.76 | DRD2 (0.44) | DRD2TDP1CAMK2DSIGMAR1MEN1 | |
| SCHEMBL4783608 | 0.76 | ALDH1A1 (0.49) | DRD2TDP1SIGMAR1MEN1GAA | |
| SCHEMBL27246689 | 0.76 | TDP1 (0.52) | DRD2MAOAMAOBCA1CA2 | |
| SCHEMBL24618412 | 0.75 | DRD2 (0.48) | DRD2TDP1CAMK2DSIGMAR1MEN1 | |
| SCHEMBL30945709 | 0.75 | DRD2 (0.48) | DRD2MAOAMAOBCA1CA2 | |
| SCHEMBL1308684 | 0.74 | DRD2 (0.55) | DRD2MAOAMAOBTDP1SIGMAR1 | |
| SCHEMBL18379444 | 0.74 | DRD2 (0.47) | DRD2CA1CA2CA12CA9 | |
| SCHEMBL13712849 | 0.73 | TDP1 (0.54) | DRD2MAOAMAOBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465613-A2 | COMBINATION OF MTP INHIBITORS OR APOB SECRETION INHIBITORS WITH FIBRATES FOR USE AS DRUGS | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003057205-A2 | COMBINATION OF MTP INHIBITORS OR APOB SECRETION INHIBITORS WITH FIBRATES FOR USE AS DRUGS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-07-17 | — | — | WO | disclosed |