Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.60 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30704375 | 0.79 | ACHE (0.60) | BAZ2BACHEGRIN1GRIN2AGRIN2D | |
| SCHEMBL3028678 | 0.78 | BAZ2B (0.57) | BAZ2BACHEGRIN1GRIN2AGRIN2D | |
| SCHEMBL30945688 | 0.77 | KDR (0.57) | BAZ2BACHEGRIN1GRIN2AGRIN2D | |
| SCHEMBL3716545 | 0.76 | BAZ2B (0.62) | BAZ2BACHEGRIN1GRIN2AGRIN2D | |
| SCHEMBL21723856 | 0.75 | BAZ2B (0.52) | BAZ2BGRIN2BGAAMEN1KMT2A | |
| SCHEMBL21723990 | 0.74 | PRMT5 (0.61) | GAAMEN1MAPTKMT2APOLB | |
| SCHEMBL3034533 | 0.74 | APAF1 (0.84) | BAZ2BAPAF1HDAC1HDAC6 | |
| SCHEMBL27246706 | 0.73 | ACHE (0.54) | BAZ2BACHEGRIN1GRIN2AGRIN2D | |
| SCHEMBL30095900 | 0.73 | ACHE (0.54) | BAZ2BACHEGRIN1GRIN2AGRIN2D | |
| SCHEMBL3028608 | 0.73 | BAZ2B (0.55) | BAZ2BACHEGRIN1GRIN2AGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | DCAF1, DDB1, CUL4A | BAZ2B 98/4885ACHE 4434/4885GRIN1 2498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.