SCHEMBL30945779

SCHEMBL30945779

CCCCCCOC(=O)[C@H](COC(C)(C)C)N=C=O

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.39
EPHX1 P07099 1/20 0.37
TSHR P16473 3/20 0.36
HCAR2 Q8TDS4 1/20 0.35
RAD52 P43351 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
FAAH O00519 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
ACHE P22303 6/20 0.33
HTR2C P28335 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30945794 1.00 NAAA (0.39) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL30945834 0.88 MAPK1 (0.32)
SCHEMBL16542989 0.82 NAAA (0.46) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL27529753 0.80 NAAA (0.43) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL2289546 0.78 NAAA (0.50) NAAAEPHX1TSHRRAD52NPSR1
SCHEMBL11438850 0.78 MAPT (0.43) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL2736223 0.77 MAPK1 (0.35)
SCHEMBL11443787 0.75 MAPT (0.43) NAAAEPHX1FAAH
SCHEMBL30945810 0.75 NAAA (0.44) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL16710359 0.74 ALDH1A1 (0.42) NAAAEPHX1TSHRHCAR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
CN-118382612-A Method for producing blocked isocyanate compound and method for producing isocyanate compound 旭化成株式会社 2024-07-23 CN disclosed
CN-118215651-A Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition 旭化成株式会社 2024-06-18 CN disclosed