Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.54 |
| ▸ | TLR2 | O60603 | 4/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | QDPR | P09417 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29224145 | 1.00 | HTR2C (0.54) | HTR2CTLR2KMOSLC18A3SIGMAR1 | |
| SCHEMBL3787686 | 0.89 | KMO (0.54) | KMOSIGMAR1BRAFDRD3 | |
| SCHEMBL19862479 | 0.86 | KMO (0.64) | KMOSIGMAR1BRAFDRD3 | |
| SCHEMBL12577717 | 0.83 | HTR2C (0.58) | HTR2CTLR2KMOSLC18A3SIGMAR1 | |
| SCHEMBL25340114 | 0.82 | KMO (0.48) | KMOBRAFDRD3 | |
| SCHEMBL1273971 | 0.82 | HTR2C (0.54) | HTR2CTLR2 | |
| SCHEMBL13609464 | 0.82 | HCRTR1 (0.56) | HTR2CTLR2 | |
| SCHEMBL1633310 | 0.81 | KMO (0.71) | HTR2CTLR2KMOSLC18A3SIGMAR1 | |
| SCHEMBL28767888 | 0.81 | KMO (0.39) | HTR2CTLR2KMOBRAFDRD3 | |
| Hydrochloric Acid SCHEMBL4303987 | 0.81 | HCRTR1 (0.55) | HTR2CTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146234-A | 6,5,7,6-Tetracyclic derivatives, preparation method and application thereof | 浙江我武翼方药业有限公司 | 2024-06-07 | — | — | CN | disclosed |