Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787686 | 0.93 | KMO (0.54) | KMODRD3HDAC4HDAC2HDAC8 | |
| SCHEMBL29224145 | 0.86 | HTR2C (0.54) | KMODRD3BRAFSIGMAR1 | |
| SCHEMBL25340114 | 0.86 | KMO (0.48) | KMODRD3BRAFHCRTR1HCRTR2 | |
| SCHEMBL30945941 | 0.86 | HTR2C (0.54) | KMODRD3BRAFSIGMAR1 | |
| SCHEMBL19862476 | 0.81 | KMO (0.70) | KMODRD3HDAC4HDAC2HDAC8 | |
| SCHEMBL19865864 | 0.80 | KMO (0.59) | KMODRD3HDAC4HDAC2HDAC8 | |
| SCHEMBL5390528 | 0.80 | KMO (0.59) | KMODRD3ATM | |
| SCHEMBL9338681 | 0.80 | KMO (0.73) | KMODRD3HDAC4HDAC2HDAC8 | |
| SCHEMBL6051833 | 0.80 | KMO (0.96) | KMODRD3HDAC4HDAC2HDAC8 | |
| SCHEMBL11022782 | 0.80 | HAO1 (0.61) | HDAC8HAO1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044284-A1 | NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-02-15 | — | — | US | disclosed |
| US-20180044284-A1 | NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044284-A1 | NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS | PLG, PPARG, PKLR | KMO 359/4885DRD3 3782/4885HDAC4 3175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.