Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.83 |
| ▸ | MAOB | P27338 | 3/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273561 | 0.91 | MAOA (1.00) | MAOAMAOBALDH1A1RECQLTDP1 | |
| SCHEMBL29224140 | 0.89 | MAOA (0.68) | MAOAMAOBALDH1A1RECQLTDP1 | |
| SCHEMBL29266041 | 0.89 | MAOA (0.96) | MAOAMAOBALDH1A1RECQLTDP1 | |
| SCHEMBL9343961 | 0.89 | MAOA (0.96) | MAOAMAOBALDH1A1RECQLTDP1 | |
| SCHEMBL29191461 | 0.70 | MAOA (0.50) | MAOAMAOBALDH1A1RECQLTDP1 | |
| SCHEMBL27768231 | 0.70 | MAOA (0.50) | MAOAMAOBALDH1A1RECQLTDP1 | |
| SCHEMBL30466802 | 0.70 | MAOA (0.50) | MAOAMAOBALDH1A1RECQLTDP1 | |
| SCHEMBL29130494 | 0.68 | MAOA (0.48) | MAOAMAOBALDH1A1RECQLTDP1 | |
| SCHEMBL11088343 | 0.67 | MAOA (0.41) | MAOAMAOBALDH1A1MEN1MAPT | |
| SCHEMBL10781942 | 0.67 | MAOA (0.64) | MAOAMAOBTDP1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146234-A | 6,5,7,6-Tetracyclic derivatives, preparation method and application thereof | 浙江我武翼方药业有限公司 | 2024-06-07 | — | — | CN | disclosed |