Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768230 | 0.89 | MAOA (0.52) | MAOAMAOBALDH1A1 | |
| SCHEMBL30945992 | 0.70 | MAOA (0.83) | MAOAMAOBMEN1ALDH1A1MAPT | |
| SCHEMBL10997303 | 0.68 | PPARA (0.30) | — | |
| SCHEMBL9273561 | 0.67 | MAOA (1.00) | MAOAMAOBMEN1ALDH1A1MAPT | |
| SCHEMBL29266041 | 0.65 | MAOA (0.96) | MAOAMAOBMEN1ALDH1A1MAPT | |
| SCHEMBL9343961 | 0.65 | MAOA (0.96) | MAOAMAOBMEN1ALDH1A1MAPT | |
| SCHEMBL29191461 | 0.65 | MAOA (0.50) | MAOAMAOBMEN1ALDH1A1MAPT | |
| SCHEMBL29130494 | 0.64 | MAOA (0.48) | MAOAMAOBMEN1ALDH1A1MAPT | |
| SCHEMBL28124678 | 0.63 | MAPT (0.31) | MAOAMAOBMAPT | |
| SCHEMBL29224140 | 0.63 | MAOA (0.68) | MAOAMAOBMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101624332-A | Novel compound with antitumor activity and application thereof | GUANZHOU INST OF BIOMEDICINE A | 2010-01-13 | — | — | CN | claimed |
| CN-101624332-B | Novel compound with antitumor activity and application thereof | GUANZHOU INST OF BIOMEDICINE AND HEALTH CHINESE ACADEMY OF SCIENCE | 2012-11-21 | — | — | CN | disclosed |
| CN-101624332-A | Novel compound with antitumor activity and application thereof | GUANZHOU INST OF BIOMEDICINE A | 2010-01-13 | — | — | CN | disclosed |